journal of the royal society interface ranking

Examples of both peptide helices and hairpins are presented. The present review explores the relationships between folded conformations in hybrid sequences and their counterparts in all α-residue sequences. There was consistently less thrombosis and IH in the SwirlGraft than conventional shunts. Biomechanics relates the function of a physiological system to its structure. Last day 1 week 1 month all. The model quantitatively accounts for experimentally determined site-specific phosphorylation and dephosphorylation rates, differential affinities of binding proteins for the phosphorylated sites and binding protein expression levels. The high shear force observed (approx. Full Ranking List. However, long-term in vitro studies of cell-nanofibre interactions were rarely reported and successful organ regeneration using tissue engineering techniques may take months (e.g. Alpha helical coiled-coils appear in many important allosteric proteins such as the dynein molecular motor and bacteria chemotaxis transmembrane receptors. Only the overall local density, irrespective of puck type, was found to be required which offers the prospect for a more simple mechanism than had been previously considered. That was the surprising question tackled by Princeton biologists Chris Tokita and Corina ... A team of researchers at the University of Ghent has found evidence that suggests birds with white wing feathers close to the body and black wing tips get increased lift from their wing colors. Journal description. All rights reserved. In this paper, the FE model is extended to account for the probable anisotropic properties of these d-a interface phases. The quality of articles has followed a similar trajectory. In the absence of shear forces, these fibres show minimal normal adhesion. All these raw data are useless if they cannot be properly analysed, annotated, stored and displayed. Protein structure prediction is one of the major challenges in bioinformatics today. Using different mesh sizes and geometries of a gold template, hydroxyapatite nanoparticles suspended in ethanol have been electrohydrodynamically sprayed on titanium and glass substrates under carefully designed electric field conditions. The shape of the carapace protecting the body of boxfishes has been attributed an important hydrodynamic role in drag reduction and in providing automatic, flow-direction realignment and is therefore used in bioinspired design of cars. Here, we demonstrate with a mechanical model dragonfly that, despite presenting no advantage in terms of lift, flying with two pairs of wings can be highly effective at improving aerodynamic efficiency. Templates blocked contraction and scar formation by inducing a reduction in the density of contractile fibroblasts (probably myofibroblasts) and by preventing these cells to organize themselves appropriately in the wound. Journal of the Royal Society Interface is the Society's cross-disciplinary publication promoting research at the interface between the physical and life sciences. If you've ever walked past a bees nest on a hot summer day, you've probably been too focused on avoiding getting stung, rather than stopping to wonder how all those bees stay cool. Long-term viability of coronary artery smooth muscle cells on poly(L-lactide-co-ε-caprolactone) nanofibrous scaffold indicates its potential for blood vessel tissue engineering. However, tight swimming-course stabilization is paradoxical given the frequent, high-performance manoeuvring that boxfishes display in their spatially complex, coral reef territories. In this report, we uncover and elucidate a novel method that allows the easy deposition of a wide variety of predetermined topographical geometries of nanoparticles of a bioactive material on both metallic and non-metallic surfaces. The models predict that coupling of slide, bend and twist modes of the coiled-coil transmits an allosteric free energy of approximately 2kBT, consistent with experimental results. The average normalized r.m.s.d. Ranking by Popularity . Proteins from extremophiles as stable tools for advanced biotechnological applications of high social interest. Under these constraints and informed by research on Temnothorax ants, two puck sorting algorithms were tested in a combination of simulation and with real robots. Microscale behaviour. With the appropriate fore-hind wing phasing, aerodynamic power requirements can be reduced up to 22 per cent compared with a single pair of wings, indicating one advantage of four-winged flying that may apply to both dragonflies and, in the future, biomimetic micro air vehicles. Physicist Richard Feynman highlighted the importance of fluctuations in living matter when he stated, "Everything that living things do can be understood in terms of the jigglings and wigglings of atoms." Multilayers of aligned oriented PCASMCs were formed on the scaffold after two months of in vitro culture. A favourable interaction between this scaffold and PCASMCs was demonstrated by cell viability assay, scanning electron microscopy, histological staining and extracellular matrix (ECM) secretion. Although carefully collected, accuracy cannot be guaranteed. Thus, the anisotropy of the phases could effect the probable location of failure initiation, whether in the peritubular region or in the hybrid layer. scores and CPU time, the currently best-performing prediction algorithm is identified to be the I-TASSER algorithm. We found (using experimentally approved parameter values) that decreases in the TF binding rate changes the type of transition between steady state and oscillation. Biodegradable polymer nanofibres have been extensively studied as cell culture scaffolds in tissue engineering. Equally puzzling is how our ancestors managed to overcome the collective action problem and evolve strong innate preferences for cooperative behaviour. While detailed knowledge about these patterns is important to understand the anatomic and genetic aspects of glaucoma, current classification schemes are typically predominantly derived qualitatively. Sci. This review examines the nature of intramolecularly hydrogen-bonded conformations of hybrid peptides formed by amino acid residues, with a varying number of backbone atoms. While the general objective is to predict the three-dimensional structure from primary sequence, our current knowledge and computational power are simply insufficient to solve a problem of such high complexity. J. R. Soc. Finally, the stochastic simulation of the model confirms the hysteresis with switching between the two attractors, resulting in highly skewed period distributions. Here, we classify glaucomatous vision loss quantitatively by statistically learning prototypical patterns on the convex hull of the data space. In the present review, we shall outline the general approach of biomechanics. I would like to thank my colleagues on the editorial board for their role in the development of Journal of the Royal Society Interface. By linking every pair of genotypes that are mutually accessible through mutation, genotypes organize themselves into neutral networks (NNs). Based on a four-state continuous-time Markov chain, we derive a generalized nonlinear mixed-effect model for analysing the serological test data. Results from ant experiments also showed that sorting is carried out in two phases: a primary clustering episode followed by a spacing phase. Clinical trials of treatments for AD based on anti-amyloid therapy have been unsuccessful. Our analysis shows that great gerbils recovered from a plague infection are more likely to keep their antibodies to plague and survive throughout the summer-to-winter season than throughout the winter-to-summer season. Similar to gecko fibre arrays, the synthetic patch maintains contact and increases shear force with sliding. HIV recombination: What is the impact on antiretroviral therapy? This holds true ... A team of researchers from Pomona College and the Rancho Santa Ana Botanic Garden has figured out how a wild petunia plant is able to fling its seeds so far. It offers rapidity, visibility and high-quality peer review and is ranked sixth in JCR" multidisciplinary category. Popular. The experimental observations on the actin folding and unfolding pathways are collated and then re-examined from this perspective, allowing us to determine the position of the CCT intervention on the actin free-energy folding landscape. Depositing an item was governed by the distance travelled which was specific to the type of item being carried. Gecko-inspired microfibre arrays with 42 million polypropylene fibres cm(-2) (each fibre with elastic modulus 1 GPa, length 20 microm and diameter 0.6 microm) were fabricated and tested under pure shear loading conditions, after removing a preload of less than 0.1 N cm(-2). Atomic force microscopy (AFM) was used to image footprints at high resolution and to acquire measurements of interaction forces. Impact factor. Top Journals. In particular, we confirm the experimental findings that inhibition of homotype gap junctions favours migration while heterotype inhibition hinders it. The virus may spread by direct contact between animals or via fomites as well as through airborne transmission, with the latter being the most difficult to control. However, rotation invariance seems to be uniquely difficult. There thus appears to be a clear benefit from incorporating this knowledge in the design of new prediction algorithms. In this case it was Hodgkin and ... Could the division of labor in an anthill be driven by the same social dynamics governing the gap between liberals and conservatives? We show the applications of our work to several important problems in anthropology, including clustering and indexing of skulls, projectile points and petroglyphs. We used an extended Kalman filter to estimate the state of each fly, given past positions from the reconstructed fly visual hulls. Login. In particular, for spherical and ellipsoidal geometries, it is possible to determine the angular parts of these two functions as well as to obtain an explicit constraint satisfied by their radial parts.

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